Figure 1.

Mean levels ± SD of fasting glucose (A), insulin (B), FAs (C), and adiponectin (D) in patients during placebo (black bars) and Pio (white bars) treatments. The placebo values are single fasting blood samples obtained at the start of placebo treatment, while the Pio values are the means of 2 fasting blood samples obtained at the last 2 outpatient visits during treatment (either weeks 12 and 13 or weeks 12 and 15). Pio treatment was associated with reductions in plasma glucose, insulin, and FA levels, while adiponectin levels increased during Pio treatment.