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. 2023 Nov 23;12(23):4230. doi: 10.3390/foods12234230

Table 2.

The association between dietary vitamin C consumption and serum Klotho concentrations among all participants.

Dietary Vitamin C Consumption (mg/day) Percent Changes (%) and 95% CI
Model 1 p Value Model 2 p Value Model 3 p Value
Per SD increases 1.33 (0.56, 2.12) 0.001 1.54 (0.78, 2.31) <0.001 1.17 (0.37, 1.99) 0.006
Quintile 1 Ref. Ref. Ref.
Quintile 2 0.69 (−1.75, 3.19) 0.585 0.97 (−1.43, 3.44) 0.434 0.77 (−1.60, 3.20) 0.530
Quintile 3 0.68 (−1.71, 3.14) 0.581 1.18 (−1.22, 3.63) 0.342 0.51 (−1.68, 2.74) 0.653
Quintile 4 0.48 (−1.54, 2.54) 0.644 1.09 (−0.88, 3.10) 2.833 0.37 (−1.69, 2.48) 0.726
Quintile 5 4.08 (1.51, 6.72) 0.002 4.89 (2.38, 7.47) <0.001 3.66 (1.05, 6.32) 0.007
p for trend <0.001 <0.001 0.011

Note: CI: confidence interval; SD: standard deviation. Model 1 was a crude model; Model 2 was adjusted for age and sex; and Model 3 was further adjusted for BMI, PIR, ethnicity, education attainment, serum cotinine, alcohol consumption, diabetes or not, hypertension or not, eGFR, and dietary energy intake. The quintile of dietary vitamin C consumption ranges: Quintile 1: 0 to 17.10 mg/day; Quintile 2: 17.11 to 36.80 mg/day; Quintile 3: 36.81 to 70.60 mg/day; Quintile 4: 70.61 to 129.78 mg/day; and Quintile 5: 129.79 to 1617.80 mg/day. Bold indicates significance with p < 0.05.