Skip to main content
. 2023 Nov 23;24(23):16638. doi: 10.3390/ijms242316638
KSHV Kaposi’s sarcoma-associated herpesvirus
HHV8 Human herpesvirus-8
EBV Epstein–Barr virus
TRN Transcription factor or transcriptional regulatory network
IEGs Immediate-early genes
TFs Transcription factors
IL-8 Interleukin 8
CXCL8 Chemokine (C-X-C motif) ligand 8
CXCL7 Chemokine (C-X-C motif) ligand 7
CCL19 Chemokine (C-C motif) ligand 19
CXCL13 Chemokine (C-X-C motif) ligand 13
MSI Microsatellite instability
MSS Microsatellite stability
APC Adenomatous polyposis coli
KRAS Kirsten rat sarcoma virus
PIK3CA Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
SMAD4 Mothers against decapentaplegic homolog 4
TP53 Tumor protein P53
DCC Netrin receptor
SMAD Mothers against decapentaplegic
BRAF B-Raf Proto-Oncogene
Wnt Wingless-related integration site
BMP Bone morphogenetic protein
TGFβ Transforming growth factor-beta
Ras Rat sarcoma virus
ST6GALNAC1 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
CDH1 Cadherin 1
STK11 Serine/threonine kinase 11
MLH1 mutL homolog 1
MSH2 mutS homolog 2
EPCAM Epithelial cell adhesion molecule
MSH6 mutS homolog 6
PMS2 PMS1 homolog 2, mismatch repair system component
FAP Familial adenomatous polyposis
BRCA2 BReast CAncer gene 2
PALB2 Partner and localizer of BRCA2
CLDN18-ARHGAP Fusion Gene_Claudin 18-Rho GTPase-activating protein
ARID1A AT-rich interaction domain 1A
PD-L1/2 Programmed cell death ligand ½
ICIs Immune checkpoint inhibitors
CTLA-4 Cytotoxic T-lymphocyte associated protein 4
PD-1 Programmed cell death 1
LAG-3 Lymphocyte activating 3
TIM-3 Hepatitis A virus cellular receptor 2
PD-L1 CD274 molecule
ERBB2 erb-b2 receptor tyrosine kinase 2
MET Methoprene-tolerant proto-oncogene, receptor tyrosine kinase
NKX2 Ventral nervous system defective
DOK2 Docking protein 2
ALK Anaplastic lymphoma receptor tyrosine kinase
ROS1 ROS proto-oncogene 1, receptor tyrosine kinase
RET Ret proto-oncogene
ALK/EML4 Anaplastic lymphoma receptor tyrosine kinase–Echinoderm microtubule-associated protein-like 4
TTN titin
CSMD3 CUB and Sushi multiple domains 3
MUT16 MUTator 16
RYR2 Ryanodine receptor 2
BRINP3 BMP/retinoic acid inducible neural specific 3
COL11A1 Collagen type XI alpha 1 chain
GRIN2B Glutamate ionotropic receptor NMDA type subunit 2B
MUC5B Mucin 5B, oligomeric mucus/gel-forming
NLRP3 NLR family pyrin domain containing 3
TENM3 Teneurin transmembrane protein 3
NSCLC Non-small cell lung cancer
LUAD Lung adenocarcinoma
LUSC Lung squamous cell carcinoma
TCGA-STAD The Cancer Genome Atlas Stomach Adenocarcinoma
RUNX2 Runt-related transcription factor 2
SOX4 SRY-box transcription factor 4
SOX17 SRY-box transcription factor 17
BZW2 Basic leucine zipper and W2 domains 2
FOXM1 Forkhead box M1
ZBTB16 Zinc finger and BTB domain containing 16
TAL1 T-cell acute lymphocytic leukemia 1 bHLH transcription factor 1, erythroid differentiation factor
KLF4 Kruppel-like transcription factor 4
EPAS1 Endothelial PAS domain protein 1
HOXC6 Homeobox C6
ID4 Inhibitor of DNA binding 4
KLF2 Kruppel-like transcription factor 2
MEIS1 Meis homeobox 1
NR2F1 Nuclear receptor subfamily 2 group F member 1
TBX4 T-box transcription factor 4
TCF21 Transcription factor 21
TFAP2C Transcription factor AP-2 gamma
LMO2 LIM domain only 2
MNDA Myeloid cell nuclear differentiation antigen
FOXF1 Forkhead box F1
HLF HLF transcription factor, PAR bZIP family member
RFX2 Regulatory factor X2
DLX5 Distal-less homeobox 5
MYBL2 MYB proto-oncogene like 2
NR4A3 Nuclear receptor subfamily 4 group A member 3
PKNOX2 PBX/knotted 1 homeobox 2
GPRASP1 G protein-coupled receptor associated sorting protein 1
PAH Pulmonary arterial hypertension
DEGs Differentially expressed genes
CpG Cytosine–guanine dinucleotides
DNMT1 DNA methyltransferase 1
DNMT3A DNA methyltransferase 3 Alpha
DNMT3B DNA methyltransferase 3 Beta
TET Ten-eleven translocation family
FIGN Fidgetin, microtubule severing factor
HTRA3 HtrA serine peptidase 3
BDNF Brain-derived neurotrophic factor
HCN4 Hyperpolarization activated cyclic nucleotide gated potassium channel 4
STAC2 SH3- and cysteine-rich domain 2
SEPT9 Septin 9
SDC2 Syndecan 2
MGMT O-6-methylguanine-DNA methyltransferase
NDGR4 N-Myc Downstream-Regulated Gene 4 Protein
BMP3 Bone morphogenetic protein 3
VIM Vimentin
SFRP Secreted frizzled-related protein
p16 Cyclin-dependent kinase inhibitor 2A
LINE-1 Long interspersed nuclear element 1
BCAT1/IKZF1 Branched-chain amino acid transaminase 1-IKAROS family zinc finger 1
RASSF1A Ras-association domain family member 1
Wnt5A Wnt family member 5A
SFRP2 Secreted frizzled-related protein 2
DKK2 Dickkopf WNT signaling pathway inhibitor 2
PCDH10 Protocadherin 10
TMEFF2 Transmembrane protein with EGF-like and two follistatin-like domains 2
SFRP1 Secreted frizzled-related protein 1
HS3ST2 Heparan sulfate-glucosamine 3-sulfotransferase 2
CDH1/RHOA Cadherin 1-ras homolog family member A
RPRM Reprimo, TP53-dependent G2 arrest mediator homolog
ZNF793 Zinc finger protein 793
RUNX3 Runt-related transcription factor 3
PTEN Phosphatase and tensin homolog
CXXC4 CXXC finger protein 4
TIMP2 TIMP metallopeptidase inhibitor 2
COL9A2 Collagen type IX alpha 2 chain
EYA1 EYA transcriptional coactivator and phosphatase 1
ZNF365 Zinc finger protein 365
AMPH Amphiphysin
SORCS3 Sortilin-related VPS10 domain containing receptor 3
AJAP1 Adherens junctions-associated protein 1
TGFβ2 Transforming growth factor beta 2
SHOX2 Short stature homeobox 2
RASSF1A Ras-association domain family member 1
RASSF1A-RARβ2 Ras-association domain family member 1–retinoic acid receptor beta 2
SHOX2-PTGER4 Short stature homeobox 2-prostaglandin E receptor 4
p16-RARβ2 Cyclin=dependent kinase inhibitor 2A–retinoic acid receptor beta 2
DAL-1 Erythrocyte membrane protein band 4.1 like 3
EPHB6 EPH receptor B6
HS3ST2 Heparan sulfate-glucosamine 3-sulfotransferase 2
TMEM88 Transmembrane protein 88
ELMO3 Engulfment and cell motility 3
HOXA9 Homeobox A9
RARβ2 Retinoic acid receptor beta 2
CDH13 Cadherin 13
CDKN2A/P16 Cyclin-dependent kinase inhibitor 2A
CASP8 Caspase 8
TNFRSF6/Fas Fas cell surface death receptor
TRAIL-R1/DR4 TNF receptor superfamily member 10a
SCLC Small-cell carcinoma
cfDNA Cell-free DNA
ANK1 Ankyrin 1
CCND2 Cyclin D2
GATA3 GATA-binding protein 3
KCNH5 Potassium voltage gated channel subfamily H member 5
RARβ Retinoic acid receptor beta
RASSF1 Ras-association domain family member 1
CLDN1 Claudin 1
TP63 Tumor protein p63
TPX5 T-box transcription factor 5
ADHFE1 Alcohol dehydrogenase iron containing 1
HNF1B HNF1 homeobox B
EZH2 Enhancer of zeste 2 polycomb-repressive complex 2 subunit
IBD Inflammatory bowel disease
COPD Chronic obstructive pulmonary disease
PAH-LTRS PAH associated with the congenital left-to-right shunt
CSCs Cancer stem cells
NF-kB Nuclear factor kappaB
STAT3 Signal transducer and activator of transcription 3
SCFAs Short-chain fatty acids
MUC2 Mucin 2, oligomeric mucus/gel-forming
IL-6 Interleukin 6
MUC5B Mucin 5B, oligomeric mucus/gel-forming
MUC7 Mucin 7, secreted
IL-1 Interleukin 1
IL-8 Interleukin 8
TNF α Tumor necrosis factor alpha-like
GRHL2 Grainyhead-like 2 transcription factor
RhoG Ras homology growth
ZEB1 Zinc finger E-box binding homeobox 1
MHC Major histocompatibility complex
TLR Toll-like receptors
HLA-A Major histocompatibility complex, class I, A
HLA-B Major histocompatibility complex, class I, B
HLA-C Major histocompatibility complex, class I, C
CD8+ T cells Cytotoxic T lymphocytes
HLA-DP Major histocompatibility complex, class II, DP
HLA-DQ Major histocompatibility complex, class II, DQ
HLA-DR Major histocompatibility complex, class II, DR
CD4+ T cells Helper T lymphocytes
TSA Tumor-specific antigen
CTLA4 Cytotoxic T-lymphocyte-associated protein 4
APOBEC Apolipoprotein B mRNA-editing enzyme, catalytic polypeptide 3
PAMPs Pathogen-associated molecular patterns
PRRs Pattern-recognition receptors
RLRs Retinoic acid-inducible gene-I (RIG-I)-like receptors
ALRs Melanoma-2 (AIM2)-like receptors
CLRs C-type lectin receptors
NLRs Nucleotide oligomerization domain (NOD)-like receptors
MAVS Mitochondrial antiviral-signaling protein
TBK1 TANK-binding kinase 1
IKKε Nuclear factor kappaB kinase-ε
IRF3 Interferon regulatory factor 3
IRF7 Interferon regulatory factor 7
CRD Carbohydrate-recognition domain
CTLD C-type lectin-like domain
Dectin-1 C-type lectin 1
ITAM Immunoreceptor tyrosine-based activation motif
DC-SIGN DC-specific ICAM3-grabbing non-integrin
NAIP NLR family apoptosis inhibitory protein
CIITA Class II major histocompatibility complex transactivator
HETE Cytochrome P450 family 4 subfamily F member 2
TP1 Transition protein 1
TIR Toll/IL-1R domain