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. 2023 Nov 27;24(23):16798. doi: 10.3390/ijms242316798

Figure 4.

Figure 4

The drug repositioning algorithm based on a molecular pathway. The information about mHTT interactors can be obtained via in silico methods such as text mining and a database search. Identifying molecular pathways is necessary to link disease genes, proteins, and pathways to known drugs. The search for pathway-associated drugs can be performed in such databases as DrugBank, gene2drug, and KEGG DRUG.