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. 2023 Nov 21;12(23):7215. doi: 10.3390/jcm12237215

Table 2.

Different variables related to the biological therapy (naïve for biologics, multifailure for biologic drug, treatment interruption, type of interleukin inhibitors, drug distribution) are plotted in relation to different age groups. In bold significant value (p < 0.05).

Naive for Biologic Multifailure for Biologic Drug
Age Group No Yes p Age Group No Yes p
>65 41.37% 58.63% 0.008 >65 97.84% 2.16% 0.044
65–41 38.02% 61.98% 65–41 99.48% 0.52%
40–26 27.95% 72.05% 40–26 100% 0%
<26 22.5% 77.5% <26 100% 0%
Treatment interruption Type of interleukin inhibitors
Age group No Yes p Age group IL-17 IL-23 p
>65 77.34% 22.66% 0.259 >65 62.95% 37.05% 0.005
65–41 81.08% 18.92% 65–41 63.54% 36.46%
40–26 84.47% 15.53% 40–26 55.9% 44.1%
<26 85% 15% <26 37.5% 62.5%
Drug distribution
Age group Risankizumab Guselkumab Secukinumab Brodalumab Tildrakizumab Ixekizumab p
>65 17.63% 2.88% 25.9% 19.42% 16.55% 17.63% <0.001
65–41 22.92% 6.6% 26.56% 17.19% 6.94% 19.79%
40–26 27.33% 11.8% 16.77% 24.22% 4.97% 14.91%
<26 27.5% 22.5% 7.5% 25% 12.5% 5%