Table 3.
Local or Combined Event Total Cohort (N = 41) |
Local or Combined Event HR Group (N = 22) |
|||||
---|---|---|---|---|---|---|
No (N = 32) | Yes (N = 9) | p | No (N= 16) | Yes (N =6) | p | |
Number of IDRFs | 1 (1–2.75) |
2 (2–4) |
0.04 | 2 (1–3) |
2 (1.75–2.75) |
>0.05 |
N-MYC (N) −|+ | 27|5 | 7|2 | >0.05 | 11|5 | 4|2 | >0.05 |
Preoperative Tumor Volume (mL) | 35.3 (7.5–73.2) |
23.7 (11.7–192.8) |
>0.05 | 35.3 (11.0–60.2) |
27.7 (12.1–497.4) |
>0.05 |
CME|IME (N) | 24|8 | 6|3 | >0.05 | 12|4 | 5|1 | >0.05 |
Histological regression (N) 1|2|3|4 | 0|2|2|28 | 0|0|0|9 | >0.05 | 0|1|2|13 | 0|0|0|6 | >0.05 |
RD by MRI (N) −|+ | 24|8 | 1|8 | 0.0004 | 13|3 | 1|5 | 0.005 |
Postoperative Tumor Volume (mL) RD by MRI −|+ |
0|2.7 (0)|(1.2–7.1) |
0|1.5 (0)|(0.4–6.4) |
>0.05 | 0|1.4 (0)|(0.5–8.4) |
0|1.8 (0)|(0.7–5.5) |
>0.05 |
Note: IDRFs = image-defined risk factors; CME = complete macroscopic resection; RD = residual disease; numbers in parenthesis are interquartile range.