Skip to main content
. 2023 Nov 22;28(23):7701. doi: 10.3390/molecules28237701

Figure 6.

Figure 6

LAS inhibited in vivo MDA-MB-231 xenograft tumor growth. A xenograft model was established by subcutaneous inoculation of MDA-MB-231 cells into BALB/c nude mice mammary fat pads. When the average tumor volumes reached 120 mm3, mice were randomly divided into four groups and administrated with vehicle (5% of Cremophor EL, 5% of ethanol in saline), LAS-LD (5 mg/kg), or LAS-HD (10 mg/kg) daily, or docetaxel (10 mg/kg) via i.p. injection. The treatment period lasted for 20 days and all mice were sacrificed. (A) Tumor volumes were measured throughout the experimental period. (B) Images of tumors at the end of experiment. (C) Mouse body weights throughout the experimental period. (D) Tumor weights at experimental endpoint. (E–J) Organ weights normalized to body weights and expressed at the percentage of body weight. Data are expressed as means ± SEM.* p < 0.05, ** p < 0.01, compared to the vehicle group.