Table 6.

Patients’ median [P25–P75] blood Phe metabolic control (µmol/L < 12 years and ≥12 years) and % of blood [Phe] within the Portuguese Consensus Recommendation according to age, PKU severity and type of treatment.

		Median µmol/L [P25–P75] <12 Years	Median µmol/L [P25–P75] ≥12 Years	Median % of Blood Phe Levels within Target Range
Age	<12 years (n = 18)	294 [234–354]	--	65 [50–83.0]
	≥12 years (n = 81)	--	450 [270–600]	61 [15.4–100]
PKU severity	HPA (n = 24)	247 [234–279]	217 [186–249]	100 [98.3–100]
	Mild (n = 48)	331 [257–360]	462 [313–553]	57 [22.7–92.8]
	Classical (n = 27)	--	610 [462–806]	17 [0–55.9]
Type of treatment	Diet only (n = 82)	295 [236–344]	462 [240–636]	59 [15.5–100]
	Diet + BH4 (n = 17)	296 [266–325]	421 [347–503]	77 [50.9–94.1]

Abbreviations: PKU—phenylketonuria; HPA—hyperphenylalaninemia; BH4—tetrahydrobiopterin; Phe—phenylalanine.