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. 2023 Nov 23;12(23):3945. doi: 10.3390/plants12233945

Table 4.

Safety and toxicity studies of different Amorphophallus species.

Species Dose of Toxicity Study Model Outcomes References
APME and APAE tuber >2000 mg/kg Wistar mice The LD50 was above 2500 mg/kg [31]
A. paeoniifolius >1.5 g/kg Swiss albino mice Non-toxic up to 1.5 g/kg [58]
Porang (A. oncophyllus) >5000 mg/kg BW Rats Not detrimental until the maximum dose of 5000 mg/kg b.w. [107]
Porang (A. muelleri Blume) >15,000 mg/kg BW White rats (Rattus norvegicus) Greater than 15,000 mg/kg BW porang flour dosage caused liver cell damage in white rats, and hyperactivity among the female rats was also observed [108]
APME and APAE tuber >2000 mg/kg Swiss albino mice No toxicological property was reported at the doses tested [109]