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. 2023 Nov 21;28(23):7697. doi: 10.3390/molecules28237697

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Scheme 3 — (A) Pro-apoptotic effect of compound 3k on HeLa cells after 24 h of action. (B) Quantitative analysis of the pro-apoptotic effect. (C) Changes in the expression of pro-apoptotic protein Bax and anti-apoptotic protein Bcl-2 after 24 h of compound 3k action on HeLa cells. (D) Quantitative analysis graph of the expression of pro-apoptotic protein Bax and anti-apoptotic protein Bcl-2. All the above results were expressed as the mean ± SD of three independent experiments: * p < 0.05, ** p < 0.01, *** p < 0.001 compared with the control group; ### p < 0.001 compared with the cisplatin group; ▲ p < 0.05, ▲▲ p < 0.01, ▲▲▲ p < 0.001 compared with the chalcone group.