Figure 5.
(A) Effects of IBMX and DIF-1 on glucose uptake in confluent 3T3-L1 cells. Cells were incubated for 16–20 h in the presence of 0.2% DMSO (vehicle) and the indicated concentrations of IBMX or DIF-1, and the rate of glucose consumption was assessed. The data are mean ± SD of three independent experiments. * p < 0.01 versus control (by t-test). (B) Combinatorial effects of IBMX and DIF-1 on glucose uptake. Cells were incubated for 16–20 h in the presence of 0.2% DMSO (vehicle) and the indicated concentrations of MIBMX, DIF-1, or both, and the rate of glucose consumption was assessed. The data are mean ± SD of four independent experiments. * p < 0.01 versus control (by t-test); n.s., not significant (by ANOVA).
