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. 2023 Nov 23;28(23):7725. doi: 10.3390/molecules28237725

Table 1.

Regression equations, correlation coefficients and linear ranges of demethyleneberberine in different mixed matrices of rats and mice.

Matrix Regression Equations Correlation Coefficient (r2) Linear Range (ng/mL)
Plasma Y = 227.71 X + 9.788 0.9984 0.5–1000
Heart Y = 867.95 X + 15.193 0.9994 1–1000
Liver Y = 770.17 X + 6.9004 0.9998 1–1000
Spleen Y = 271.01 X + 16.991 0.9940 1–1000
Lung Y = 239.7 X − 6.2526 0.9983 1–1000
Kidney Y = 560.53 X + 13.146 0.9964 1–1000
Brain Y = 198.63 X + 17.806 0.9948 1–1000
Stomach Y = 418.44 X − 26.683 0.9976 3–3000
Intestine Y = 1379.2 X + 9.7943 0.9961 1–3000
Urine Y = 363.85 X + 12.913 0.9998 1–3000
Feces Y = 605.06 X − 61.477 0.9930 3–5000
Bile Y = 716.2 X − 18.949 0.9911 3–5000