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. 2023 Nov 24;28(23):7742. doi: 10.3390/molecules28237742
ACh acetylcholine
AG aminoguanidine
AGEs advanced glycation end products
AKRs Aldoketo reductases
Akt PKB = protein kinase B (serine/threonine kinase)
ALDHs Aldehyde dehydrogenases
AMPK AMP-activated kinase
Ang II (Ang-2) angiotensin II
AP argpyrimidine
apoA1 apolipoprotein A1
apoB100 apolipoprotein B100
ApoE KO apolipoprotein E knockout
ATF6 activating transcription factor 6
AT2R angiotensin II receptor type 2
BBGC bromobenzyl-glutathione cyclopentyl diester (glyoxalase-1 inhibitor)
BMCs bone marrow cells
CAD coronary artery disease
CAT catalase
CEA N7-carboxyethyl arginine
C/EBP transcription factor C/EBP
CEdG N2-carboxyethyl-20–deoxyguanosine
CEL Nε-(1-carboxyethyl)lysine = N6-(1-carboxyethyl)lysine
C. elegans Caenorhabditis elegans
CETP cholesteryl ester transfer protein
CKD chronic kidney disease
CML Nε-(1-carboxymethyl)lysine = N6-(1-carboxymethyl)lysine
CTGF connective tissue growth factor
CHD coronary heart diseases
CVD cardiovascular diseases
DAG diacylglycerol
DJ-1 (PARK7) Parkinson’s disease protein 7
DKO double knockout
3-DG 3-deoxyglucosone
3DG-H 3-DG-derived hydroimidazolones
EA.hy926 hybrid human umbilical vein endothelial cell line
ECM extracellular matrix
eNOS endothelial nitric oxide synthase
EPCs endothelial progenitor cells
ER endoplasmic reticulum
esRAGE endogenous secretory RAGE proteolytically exfoliated by metalloproteinases
FFAs free fatty acids
FL Nε-fructosyl-lysine
FPG fasting plasma glucose
Fru fructose
F4/80 EGF-like module-containing mucin-like hormone receptor-like 1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
Glc glucose
GlcNAc N-acetylglucosamine
Glo1 Glyoxalase 1
Glo1 KO Glo1 knockout
Glo2 Glyoxalase 2
GLUT glucose transporter
GO glyoxal
GPX glutathione peroxidase
GSH reduced glutathione
GSK-3 Glycogen synthase kinase-3
GSSG oxidized glutathione
HAECs human aortic endothelial cells
HbA1c hemoglobin A1c
HEK293 human embryonic kidney cells
HIF hypoxia-inducible factor
HoxA5 homeobox A5 transcription factor
HO-1 heme oxygenase 1
HSPG heparan sulfate proteoglycan
HUVECs human umbilical cord vein endothelial cells
ICAM-1 intercellular adhesion molecule 1
IFN-γ interferon gamma
IL-6 interleukin 6
IL-8 interleukin 8
IL-1β interleukin-1 β
IR insulin receptor
IRE1 inositol-requiring enzyme-1
IRS-1 insulin receptor substrate 1
KATP channel ATP-sensitive potassium channel
KRAS GTPase Kirsten Rat Sarcoma Viral Oncogene Homolog
LCAT lecithin-cholesterol acyltransferase
Mac-1 macrophage-1 antigen
Mac-2 macrophage-2 antigen
MAECs mouse aortic endothelial cells
MafA musculoaponeurotic fibrosarcoma oncogene family A
MAGEs MGO-derived AGEs
MCP-1 monocyte chemoattractant peptide-1
MDA malondialdehyde
MG-dG 3-(20–deoxyribosyl)-6,7-dihydro-6,7-dihydroxy-6/7-methylimidazo-[2,3-b]purin-9(8)one
MG-H1-3 MGO-derived hydroimidazolones 1-3
MG-H1 Nδ-(5-hydro-5-methyl-4-imidazolon-2-yl)-ornithine
MG-H2 2-amino-5-(2-amino-5-hydro-5-methyl-4-imidazolon-1-yl)-pentanoic acid
MG-H3 2-amino-5-(2-amino-4-hydro-4-methyl-5-imidazolon-1-yl)-pentanoic acid
MGO methylglyoxal
MMP-9 matrix metalloproteinase 9
MnSOD manganese superoxide dismutase
MODIC 2-ammonio-6-((2-[(4-ammonio-5-oxido-5-oxopentyl)amino]-4-methyl-4,5-dihydro-1H-imidazol-5-ylidene)amino)hexanoate
MOLD 1,3-di(Nε-lysino)-4-methyl-imidazolium
mTORC1 mammalian target of rapamycin complex 1
NAC N-acetyl cysteine
NFATc Nuclear factor of activated T-cells, cytoplasmic
NO nitric oxide
NOX NADPH oxidase
Nrf2 nuclear factor erythroid 2 related factor 2
OGTT oral glucose tolerance test
p38 MAPK p38 mitogen-activated protein kinase
PAI-1 plasminogen activator inhibitor 1
PARP poly(ADP-ribose) polymerase
Pdx1 gene coding for pancreatic duodenal homeobox-1
PDX-1 homeodomain (HD)-containing transcription factor (syn: IPF-1 (insulin promoter factor 1)
PERK double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase
PGC1α transcriptional coactivator PGC1-α
PI3K phosphatidylinositol (PI) 3-kinase
PKB/Akt protein kinase B (serine/threonine kinase)
PKC protein kinase C
p-JNK phosphorylated c-Jun NH2—terminal kinase
p-p38 phosphorylated p38 kinase
p-ERK phosphorylated extracellular signal-regulated kinase
PHLPP2 PH domain leucine-rich repeat protein phosphatase 2
PON1 paraoxonase 1
PPAR peroxisome proliferation-activated receptor
RAGE AGEs receptor
RAAS renin-angiotensin-aldosterone system
RCS Reactive carbonyl species
RONS Reactive oxygen and nitrogen species
sdLDL small dense low density lipoproteins
SD rats Sprague Dawley rats
SHR Spontaneously hypertensive rats
SNP sodium nitroprusside
SSAO semicarbazide-sensitive amine oxidase
STZ streptozotocin
sICAM-1 soluble intercellular adhesion molecule 1
SOD-(1–3) superoxide dismutase (1–3)
sPLA2 secreted phospholipase A 2
sRAGE soluble RAGE produced by alternative splicing
sVCAM-1 soluble vascular cell adhesion molecule 1
TAG triacylglycerol
TAK1 transforming growth factor-β-activated kinase 1
T1DM type 1 diabetes
T2DM type 2 diabetes
TGF-β transforming growth factor β
THP tetrahydropyrimidine
TNF-α tumor necrosis factor α
UCP-2 uncoupling protein 2
UDPGlcNAc uridine diphosphate N-acetylglucosamine
UPR unfolded protein response
VCAM-1 vascular cell adhesion molecule 1
VEGF vascular endothelial growth factor
VEGFR-2 vascular endothelial growth factor receptor 2
VSMCs vascular smooth muscle cells
8-OHdG 8-hydroxy-2-deoxyguanosine
WKY Wistar Kyoto rats