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Deletion of AhR in IECs exacerbates DSS-induced chronic colitis in mice. (A) H&E stains of distal colon of WT and AhRΔIEC mice, (B) their histological scores, and (C) MPO activity. mRNA expression normalized to GAPDH of (D) IL-1β and (E) IFNγ. Histological scores: 0—no inflammation, 1—quiescent, 2—mildly active, 3—moderately active, 4—severe. Values are mean ± standard error of mean. Data were analyzed by one-way ANOVA; * p < 0.05, *** p < 0.001, **** p < 0.0001.
