Table 1.
Baseline characteristics of the original population.
| Vitamin D | No vitamin D | p | |
|---|---|---|---|
| N | 1,068 | 6,926 | |
| Age | 72.16 (60.99, 81.89) | 66.76 (54.88, 78.34) | <0.001 |
| Gender, n | |||
| Female | 576 (53.9%) | 3,015 (43.5%) | <0.001 |
| Male | 492 (46.1%) | 3,911 (56.5%) | |
| Weight (kg) | 76.00 (63.45, 93.65) | 80.00 (66.60, 97.19) | <0.001 |
| Vital signs | |||
| HR | 88.31 (75.71, 99.29) | 88.04 (77.67, 100.85) | 0.23 |
| SBP, mmHg | 113.80 (105.43, 127.29) | 113.71 (105.09, 125.95) | 0.31 |
| DBP, mmHg | 60.92 (55.15, 67.96) | 61.92 (55.46, 69.13) | 0.02 |
| MAP, mmHg | 75.50 (69.60, 82.98) | 76.44 (70.50, 83.96) | 0.001 |
| Respiratory rate (breaths/min) | 20.40 (17.74, 23.59) | 20.23 (17.62, 23.22) | 0.25 |
| Temperature | 36.83 (36.59, 37.14) | 36.94 (36.63, 37.33) | <0.001 |
| SpO2, % | 96.61 (95.01, 98.11) | 97.07 (95.37, 98.58) | <0.001 |
| Laboratory parameters | |||
| RDW (%) | 14.9 (13.92, 16.68) | 14.61 (13.63, 16.04) | <0.001 |
| Hemoglobin, g/dl | 9.95 (8.50, 11.58) | 10.75 (9.30, 12.40) | <0.001 |
| Hematocrit, % | 30.60 (26.30, 35.53) | 32.90 (28.45, 37.75) | <0.001 |
| Platelet, 109 /L | 200.00 (133.50, 266.0) | 194.00 (135.00, 263.50) | 0.23 |
| WBC count, 109 /L | 11.60 (8.15, 15.93) | 12.10 (8.85, 16.35) | 0.005 |
| Anion gap, mg/dl | 15.00 (13.00, 17.50) | 15.00 (13.00, 17.50) | 0.9 |
| Bicarbonate, mg/dl | 22.50 (19.75, 26.00) | 22.50 (19.50, 25.50) | <0.001 |
| Bun, mg/dL | 26.00 (17, 45) | 23 (15, 38) | <0.001 |
| Calcium, mg/dL | 8.30 (7.83, 8.80) | 8.20 (7.7, 8.7) | <0.001 |
| Chloride, mmol/L | 102.50 (98, 106) | 104 (100, 108) | <0.001 |
| Creatinine mg/dl | 1.20 (0.8, 1.98) | 1.1 (0.8, 1.8) | 0.33 |
| Glucose, mmol/L | 136.50 (112, 175.75) | 137.00 (114, 175) | 0.11 |
| Sodium, mg/dl | 138 (135, 141.5) | 139 (136, 141.5) | 0.004 |
| Potassium, mg/dl | 4.20 (3.85, 4.65) | 4.20 (3.85, 4.65) | 0.72 |
| INR | 1.3 (1.1, 1.65) | 1.3 (1.1, 1.65) | 0.07 |
| PT | 14.2 (12.55, 17.95) | 14.1 (12.5, 17.15) | 0.17 |
| Severity of illness | |||
| SOFA score | 7 (4, 10) | 7 (5, 11) | <0.001 |
| APS III score | 58.00 (44, 79) | 60 (43, 82) | 0.23 |
| OASIS | 37 (31, 43) | 39 (32, 45) | <0.001 |
| Comorbidities | |||
| Myocardial infarct, n | 189 (17.7%) | 1,260 (18.2%) | 0.70 |
| Congestive heart failure, n | 473 (44.3%) | 2,348 (33.9%) | <0.001 |
| Rheumatic disease, n | 73 (6.8%) | 213 (3.1%) | <0.001 |
| Chronic pulmory disease, n | 404 (37.8%) | 2,242 (32.4%) | <0.001 |
| Peptic ulcer disease, n | 31 (2.9%) | 213 (3.1%) | 0.76 |
| Liver disease, n | 188 (17.6%) | 1,218 (17.6%) | 0.99 |
| Diabetes, n | 388 (36.3%) | 2020 (29.2%) | <0.001 |
| Renal disease, n | 323 (30.2%) | 1,496 (21.6%) | <0.001 |
| Malignant cancer, n | 185 (17.3%) | 1,099 (15.9%) | 0.23 |
| Ventilator use, n | 529 (49.5%) | 4,497 (64.9%) | <0.001 |
| RRT use, n | 75 (7%) | 443 (6.4%) | 0.44 |
| Vasopressor use, n | 142 (13.3%) | 1,167 (16.8%) | 0.003 |
| Mortality | |||
| In-hospital mortality, n | 226 (21.2%) | 1784 (25.8%) | 0.001 |
| ICU-mortality, n | 126 (11.8%) | 1,303 (18.8%) | <0.001 |