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. 2023 Jul 13;14(1):101217. doi: 10.1016/j.jceh.2023.07.004

Table 3.

Donor Evaluation Protocol in Deceased Donor Liver Transplantation.

  • Identification of prospective organ donors: Identification of the cause of coma and exclusion of malignancies and active sepsis

  • Basic investigations: Blood counts and metabolic parameters, cultures, blood grouping, viral serologies (HBsAg, nti HCV, Total Anti HBc, HIV, CMV serology), ultrasound abdomen

  • Donor maintenance:
    • Appropriate antibiotic therapy
    • Inotropes/fluids to aim for target MAP >60 mmHg
    • Urine output >1 mL/kg/h
    • Temperature >35 °C
    • Correct hypernatremia to aim for serum sodium <150 mEq/dL:
      • In cases of hypotension, vasopressin should be started at a dose of 0.01–0.04 IU/min.
      • In cases of significant hypernatremia without hypotension, desmopressin can be used.
    • Normal arterial blood lactate
    • PaO2 >80 mm Hg
    • Hemoglobin >7 gm/dL
    • Correction of hypoglycemia
    • High-dose corticosteroids
    • Thyroxin replacement
  • Confirmatory tests for brainstem death & consent

CMV, cytomegalovirus; HBc, hepatitis B core; HBsAg, hepatitis B surface antigen; HCV, hepatitis C virus; HIV, human immunodeficiency virus.