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. 2023 Oct 13;59(9):684–696. doi: 10.1007/s11626-023-00803-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Figure 3. — Kidney pathology and ECM protein deposition in mice. (A) HE, PAS, and Masson staining of mice renal cortex (× 400), glomerular atrophy, renal tubular dilatation, thickening of renal tubular and glomerular basement membrane, collagen fiber deposition. (B) Quantification of collagen fibers of Masson stained in mouse renal cortex. (C) Expression of extracellular matrix protein in mice of each group and quantification of extracellular matrix protein like FN (a), collagen Ι (b), vimentin (c), and TGFβ (d). Values are the means ± SD. *p < 0.05, ***p < 0.001 vs. control group; #p < 0.05, ##p < 0.01, ### p < 0.001, vs. UUO group.

Inline graphic — Kidney pathology and ECM protein deposition in mice. (A) HE, PAS, and Masson staining of mice renal cortex (× 400), glomerular atrophy, renal tubular dilatation, thickening of renal tubular and glomerular basement membrane, collagen fiber deposition. (B) Quantification of collagen fibers of Masson stained in mouse renal cortex. (C) Expression of extracellular matrix protein in mice of each group and quantification of extracellular matrix protein like FN (a), collagen Ι (b), vimentin (c), and TGFβ (d). Values are the means ± SD. *p < 0.05, ***p < 0.001 vs. control group; #p < 0.05, ##p < 0.01, ### p < 0.001, vs. UUO group.