Table 3.
Analysis of PD-L1/PD1 in Oral leukoplakia.
| Mild | Moderate/severe | Total | p value | |
|---|---|---|---|---|
| Frequency | 11 | 14 | 25 | |
| PD-L1 positive dysplastic basal epithelial cells (labelling index) | 1 (9.1%) | 4 (28.6%) | 5 (20.0%) | 0.227 |
|
PD-L1 negative Tumour epithelial cells (labelling index) |
10 (90.9%) | 10 (71.4%) | 20 (80.0%) | |
| PD-L1 positive TAF (SID score) | 4 (36.4%) | 14 (100%) | 18 (72.0%) | 0.001 |
| PD-L1 negative TAF (SID score) | 7 (63.6%) | 0 (0%) | 7 (28.0%) | |
| SID score of PD L1 positive TAFs (mean ± SD) | 0.82 ± 1.168 | 2.86 ± 1.167 | 0.000 | |
| PD-1 positive TILs (labelling index) | 8 (72.7%) | 14 (100%) | 22 (88%) | 0.037 |
| PD-1 negative TILs (labelling index) | 3 (27.3%) | 0 (0%) | 3 (12.0%) | |
| H-score of PD-1 positive TILs (mean ± SD) | 54.73 ± 73.987 | 84.57 ± 61.405 | 0.282 |
Significant values are in bold.