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. 2023 Nov 20;9(12):e22409. doi: 10.1016/j.heliyon.2023.e22409

Table 4.

Diagnostic performances of strategies trained with 80 % of the total dataset (epoch size = 150).

Strategy Fold 1 (n = 925) Fold 2 (n = 925) Fold 3 (n = 925) Fold 4 (n = 925) Fold 5 (n = 926) Overall (n = 4626)
AUC 1. Original 0.7248 0.8123 0.7982 0.8595 0.7814 0.7952
2. Class weight (1:0) 0.7236 0.8071 0.8045 0.8478 0.7897 0.7945
3. × 10 data (positive only) 0.7687 0.8228 0.8458 0.8568 0.7838 0.8156
4. × 10 data (all) 0.7479 0.8135 0.8446 0.8677 0.7528 0.8053
Sensitivity 1. Original 0.1750 0.4000 0.2500 0.3250 0.2875 0.2875
2. Class weight (1:0) 0.4250 0.3750 0.6000 0.3125 0.2375 0.3900
3. × 10 data (positive only) 0.5125 0.6000 0.6750 0.6500 0.3625 0.5600
4. × 10 data (all) 0.1625 0.3125 0.2625 0.2500 0.2125 0.2400
Specificity 1. Original 0.9882 0.9751 0.9645 0.9870 0.9775 0.9785
2. Class weight (1:0) 0.8533 0.9503 0.8568 0.9834 0.9846 0.9257
3. × 10 data (positive only) 0.8686 0.8911 0.8249 0.8911 0.9610 0.8873
4. × 10 data (all) 0.9834 0.9846 0.9751 0.9976 0.9894 0.9860
PPV 1. Original 0.5833 0.6038 0.4000 0.7027 0.5476 0.5675
2. Class weight (1:0) 0.2152 0.4167 0.2840 0.6410 0.5938 0.4301
3. × 10 data (positive only) 0.2697 0.3429 0.2673 0.3611 0.4677 0.3418
4. × 10 data (all) 0.4815 0.6579 0.5000 0.9091 0.6538 0.6405
NPV 1. Original 0.9267 0.9450 0.9314 0.9392 0.9355 0.9356
2. Class weight (1:0) 0.9400 0.9414 0.9577 0.9379 0.9318 0.9418
3. × 10 data (positive only) 0.9495 0.9592 0.9640 0.9641 0.9410 0.9556
4. × 10 data (all) 0.9254 0.9380 0.9332 0.9336 0.9300 0.9320
Accuracy 1. Original 0.9178 0.9254 0.9027 0.9297 0.9179 0.9187
2. Class weight (1:0) 0.8162 0.9005 0.8346 0.9254 0.9201 0.8794
3. × 10 data (positive only) 0.8378 0.8659 0.8119 0.8703 0.9093 0.8590
4. × 10 data (all) 0.9124 0.9265 0.9135 0.9330 0.9222 0.9215

AUC, area under the curve; PPV, positive predictive value; NPV, negative predictive value.