Table 2.
Body weight, glucose control, CGM outcomes, lipids, BP and physical activity variables after magnesium and placebo treatment
| Variable | Magnesium | Placebo | p value |
|---|---|---|---|
| General characteristics | |||
| Weight, kg | 92.5±3.9 | 93.2±4.1 | 0.142 |
| BMI, kg/m2 | 30.9±1.2 | 31.1±1.3 | 0.160 |
| Glucose control | |||
| HbA1c, mmol/mol | 57±2 | 58±2 | 0.851 |
| HbA1c, % | 7.4±0.2 | 7.4±0.2 | |
| Insulin dose, U/daya | 44±6 | 44±7 | 0.869 |
| CGMa | |||
| Mean glucose concentration, mmol/l | 9.4±0.5 | 9.4±0.4 | 0.920 |
| CV, % | 26±1 | 27±2 | 0.247 |
| Hypoglycaemic events, yes | 5 (36) | 4 (29) | 0.558 |
| Time in range, min | 956±91 | 937±76 | 0.832 |
| Time above range, min | 470±88 | 495±76 | 0.773 |
| Lipids | |||
| Total cholesterol, mmol/l | 4.3±0.2 | 4.2±0.3 | 0.483 |
| Triglycerides, mmol/l | 2.3±0.5 | 1.8±0.3 | 0.261 |
| LDL, mmol/la | 2.1±0.2 | 2.1± 0.2 | 0.627 |
| HDL, mmol/l | 1.14±0.08 | 1.20±0.09 | 0.026 |
| BP | |||
| Systolic BP, mmHg | 135±3 | 135±5 | 0.916 |
| Diastolic BP, mmHg | 68±2 | 68±3 | 0.817 |
| Physical activityb | |||
| Sitting time, h | 10.5±0.3 | 10.2±0.4 | 0.219 |
| Active time, h | 4.2±0.4 | 4.7±0.5 | 0.098 |
| LIPA, min | 204±19 | 234±29 | 0.085 |
| MVPA, min | 47±7 | 46±6 | 0.714 |
| Step count, n | 6038±827 | 6007±746 | 0.925 |
Data are presented as mean ± SEM or n (%)
Hypoglycaemic events are expressed as a binary outcome. Other CGM and physical activity data are expressed as mean per day
an=12
bn=13
LIPA, light physical activity; MVPA, moderate-to-vigorous physical activity