Table 1.
Baseline Characteristics.
| Intervention Group (n = 26) | Control Group (n = 24) | P-Value | |
|---|---|---|---|
| Gender (male:female)b | 11:15 | 13:11 | 0.402 |
| Diagnosis | 0.423 | ||
| Biliary atresia | 18 | 14 | |
| Alagille's syndromea | 4 | 6 | |
| PFIC type IIIa | 3 | 0 | |
| Caroli's diseasea | 0 | 1 | |
| Choledocal cysta | 1 | 3 | |
| Age (month) | 23 ± 31 | 17 ± 14 | 0.992 |
| Body weight (kg)d | 8.2 ± 4.3 | 7.3 ± 1.7 | 0.954 |
| Height (cm)d | 73 ± 16 | 70 ± 7.5 | 0.838 |
| MAC (cm)d | 11.44 ± 1.42 | 10.67 ± 1.33 | 0.137 |
| Nutritional status | 0.874 | ||
| Severely malnourish | 20 | 18 | |
| Undernourished | 6 | 6 | |
| RDA (%) | 104 ± 31 | 92 ± 24 | 0.147 |
| PELD scorec | 18 ± 4 | 17 ± 4 | 0.456 |
| Hb (g/dL)c | 9.3 ± 1.2 | 8.9 ± 1.5 | 0.260 |
| Platelet ( × 103/μL)c | 188,231 ± 79,257 | 236,708 ± 107,036 | 0.074 |
| Leukocyte ( × 103/μL)d | 10880 ± 5279 | 11627 ± 5838 | 0.281 |
| Basophil (%)d | 0.6 ± 0.3 | 0.5 ± 0.3 | 0.449 |
| Eosinophild | 2.5 ± 2.1 | 1.6 ± 0.9 | 0.109 |
| Neutrophil (%)c | 47.5 ± 14.5 | 51.6 ± 11.9 | 0.290 |
| Lymphocyte (%)c | 41.6 ± 15.2 | 38.8 ± 12.1 | 0.474 |
| Monocytec | 7.75 ± 2.17 | 7.51 ± 2.28 | 0.708 |
| ANCd | 5151.05 ± 3161.80 | 6471.26 ± 3547.57 | 0.140 |
| Prothrombin time (second)c | 12.8 ± 1.5 | 13.0 ± 1.7 | 0.655 |
| INRd | 1.23 ± 0.17 | 1.25 ± 0.17 | 0.409 |
| AST (U/L)d | 249 ± 143 | 206 ± 180 | 0.057 |
| ALT (U/L)d | 139 ± 92 | 120 ± 126 | 0.087 |
| Albumin (g/dL)c | 2.93 ± 0.46 | 3.00 ± 0.37 | 0.545 |
| Total bilirubin (mg/dL)d | 19.73 ± 7.00 | 20.64 ± 8.20 | 0.641 |
| Direct bilirubin (mg/dL)d | 15.32 ± 5.79 | 15.86 ± 6.48 | 0.698 |
| Indirect bilirubin (mg/dL)c | 4.71 ± 1.99 | 4.78 ± 2.01 | 0.901 |
| GGT (U/L)d | 317.92 ± 309.42 | 336.63 ± 399.78 | 0.977 |
| TNF-αd | 1.47 ± 0.20 | 1.47 ± 0.19 | 0.938 |
| IL-10d | 0.49 ± 0.13 | 0.48 ± 0.11 | 0.801 |
| HGFd | 0.41 ± 0.08 | 0.41 ± 0.10 | 0.627 |
PFIC = progressive familial intrahepatic cholestasis; MAC = mid-arm circumference; RDA = recommended dietary allowance; PELD = pediatric end-stage liver disease; Hb = hemoglobin; ANC = absolute neutrophil count; INR = international normalized ratio; AST = aspartate aminotransferase; ALT = alanine aminotransferase; GGT = Gamma-glutamyl transferase, TNF-α = tumor necrosis factor-α, ΙL-10 = interleukin-10, HGF = hepatocyte growth factor.
categorical data calculated as oen group.
n.
normally distributed data.
Skewed data