Table 3.

Effect of Granulocyte Colony-stimulating Factor Administration to Liver Function Tests.

	Intervention group (n = 26)	Control group (n = 24)	P-value∗	P-value∗∗
AST
Day 0a	249 ± 143	206 ± 180	0.057
Day 6a	211 ± 100	204 ± 181	0.153
Day 18a	257 ± 202	213 ± 166	0.264
Day 30	257 ± 145	172 ± 93	0.018
Day 60	212 ± 101	193 ± 110	0.525
Day 90	198 ± 101	187 ± 108	0.720	0.102
ALT
Day 0a	139 ± 92	120 ± 126	0.087
Day 6a	118 ± 64	120 ± 128	0.180
Day 18a	141 ± 114	125 ± 118	0.277
Day 30a	131 ± 72	106 ± 96	0.109
Day 60a	113 ± 53	119 ± 99	0.541
Day 90a	111 ± 56	115 ± 94	0.683	0.038
Albumin
Day 0	2.93 ± 0.46	3.00 ± 0.37	0.545
Day 6	3.06 ± 0.41	3.19 ± 0.38	0.271
Day 18	2.96 ± 0.40	3.03 ± 0.39	0.538
Day 30	3.00 ± 0.41	2.98 ± 0.44	0.903
Day 60	2.90 ± 0.36	2.94 ± 0.43	0.732
Day 90	2.98 ± 0.39	2.90 ± 0.51	0.9524	0.757
Bilirubin Total
Day 0a	19.73 ± 7.00	20.64 ± 8.20	0.641
Day 6a	19.64 ± 7.67	21.03 ± 8.48	0.351
Day 18a	19.70 ± 7.41	19.99 ± 7.82	0.816
Day 30a	20.95 ± 7.85	20.61 ± 8.28	0.961
Day 60	21.93 ± 8.77	20.22 ± 8.53	0.488
Day 90	21.66 ± 8.89	2183 ± 9.30	0.948	0.396

∗P-value for independent t-test (normally distributed data)/Mann–Whitney test (skewed data) showed the comparison between intervention and control group.

∗∗P-value for analysis of variance test showed the comparison between repeated measures.

ALT = alanine aminotransferase; AST = aspartate aminotransferase.

^aSkewed data.