Table 2.
The association between the lipoprotein(a) and risk of mildly reduced eGFR
| Lipoprotein(a) levels | OR (95%CI) | |||
|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Model 4 | |
| Tertile1 | 1.00(Ref) | 1.00(Ref) | 1.00(Ref) | 1.00(Ref) |
| Tertile2 | 1.41(1.02–1.97) | 1.42(1.02–1.99) | 1.62(1.15–2.29) | 1.68(1.17–2.41) |
| Tertile3 | 1.60(1.14–2.23) | 1.62(1.16–2.26) | 1.89(1.33–2.69) | 1.80(1.24–2.60) |
| P for trend | 0.0047 | 0.0038 | 0.0005 | 0.0025 |
| Per SD increase in ln-Lp(a) | 1.19(1.04–1.37) | 1.20(1.05–1.37) | 1.27(1.10–1.47) | 1.23(1.05–1.43) |
Model1: adjusted for age, sex, BMI
Model2: further adjusted for current smoker (yes/no), current drinker (yes/no) and physical activity based on Model1
Model3: further adjusted for SBP, TG, TC, LDL-c, ALT, AST, FPG based on Model2
Model4: further adjusted for UA based on Model3
Abbreviations: BMI Body mass index, SBP Systolic blood pressure, ALT Alanine aminotransferase, AST Aspartate aminotransferase, TC Total cholesterol, TG Triglycerides, LDL-c Low-density lipoprotein cholesterol, UA Uric acid, FPG Fasting plasma glucose