Table 3.

Differences in Inflammatory Biomarker Levels between Subclasses 1 and 2

Biomarkers (pg/mL)	Subclass 1	Subclass 2	False discovery rate (FDR) adjusted p value†
PAI1	500 (224–887)	200 (94–308)	0.013*
IL4	7919 (3270–11897)	4510 (1770–10910)	0.32
IL6	148 (49–699)	15 (9–52)	< 0.001*
IL8	34 (24–217)	14 (13–20)	< 0.001*
IL10	13 (10–72)	10 (7–18)	0.027*
ANG2	6936 (3255–8587)	3414 (1901–6216)	0.035*
Thrombomodulin	4891 (4234–6531)	4144 (3389–5651)	0.15
TFPI	12,027 (7262–18,706)	13,440 (7036–17308)	0.72
TREM1	489 (330–578)	325 (258–427)	0.044*
P-selectin	6414 (4880–8740)	6878 (4623–8885)	0.93
ICAM1	130,000 (97,558- 193,000)	113,000 (80,346- 164,000)	0.36
TNFR-1	1833 (1466–2284)	1106 (932–1296)	< 0.001*

Data presented as median (IQR)

*Significant FDR values are noted with an asterisk

^†P values computed by Wilcoxon rank-sum test and adjusted by FDR criterion