Table 4.

Adverse events

	Ramipril (N = 79)	Placebo (N = 35)
Participants who experienced any adverse event, n (%)	21 (27)	10 (29)
Total serious adverse eventsa, n (% of total adverse events)	2 (5)	0 (0)
Grade 1 adverse events, n (% of total adverse events)	27 (73)	15 (79)
Grade 2 adverse events, n (% of total adverse events)	8 (22)	2 (11)
Grade 3 adverse events, n (% of total adverse events)	1 (3)	0 (0)
Grade 4 adverse events, n (% of total adverse events)	0 (0)	0 (0)
Grade 5 adverse events, n (% of total adverse events)	1 (3)	0 (0)
Grade missing, n (% of total adverse events)	0 (0)	2 (11)
Adverse events, n	37	19
Allergic reaction/angioedema, n	1	0
Abnormal liver function test, n	3	1
Hyperkalemia, n	0	0
Acute kidney injury, n	1	0
Hypotension, n	0	0

^aGrade ≥ 3 toxicity