Table 1.

Receptor binding profiles of several major cannabinoids on CB1, CB2 and other putative cannabinoid receptors.

Drug	CB1 (Ki, nM)	CB2 (Ki, nM)	GPR55 (EC50, nM)	TRPV1 (EC50, μM)	PPARγ (EC50, μM)
Anandamide (AEA)	61–543	279–1940	18	0.16–1.15	8–10
2-Arachidonoylglycerol (2-AG)	58–472	145, 1400	3	8.4–26	10–30
Δ9-Tetrahydrocannabinol (THC)	5.05–80.3	3.13–75.3	8	>100	0.3
WIN55,212-2 (WIN)	1.89–123	0.28–16.2	N.D.	>100	10
CP55940	0.5–5.0	0.69–2.8	5	>100	10
HU-210	0.06–0.73	0.17–0.52	26	1.2	N.D.

Based on Pertwee (2008a) and Pertwee et al. (2010).