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. 2023 Dec 8;11:20503121231216585. doi: 10.1177/20503121231216585

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© The Author(s) 2023

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Gross morphology of ACF (white arrow) in colon tissues of rats. (a) normal negative rats; (b) cancer rats treated only with AOM; (c) reference rats received 35 mg/kg of 5-FU; (d and e) rats received 30 and 60 mg/kg PN. (Magnification, 10×). The ACF incidence was significantly down-regulated in PN-treated rats compared to cancer control rats.