Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Dec 8;11:20503121231216585. doi: 10.1177/20503121231216585

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 5. — Microscopic views of cross-sectioned colonic tissues in rats. (a) Normal controls had clear mucus and goblet cells (yellow star), the appearance of normal glands with round nuclei in the basal location in signet cells (orange arrow) away from the lumen (black double arrow); (b) cancer control rats received only AOM had marked nuclear atypia (elongated and stratified nucleus) multi-stratified layers of cell with nucleus abnormalities (orange arrow) in the lumen filled ACF (green star) and numerous leukocyte infiltration (blue arrow); (c) rats treated with 35 mg/kg of 5-FU had an almost same glandular appearance as normal control with round and semi-elongated nucleus (orange arrow) at the basal location with reduced ACF (green star); (d and e) rats received 30 and 60 mg/kg PN, showed fewer multi-layer cells, less nucleus abnormalities (orange arrow) and fewer leukocyte infiltration (blue arrow) compared to cancer controls. H&E. (Magnification, 100×).