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. 2023 Dec 8;11:20503121231216585. doi: 10.1177/20503121231216585

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© The Author(s) 2023

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 6. — The immunohistochemical appearance of Bax expression in different colon tissues: (a) normal negative rats; (b) cancer rats had reduced Bax proteins and severe mucosal injury; (c) reference rats (35 mg/kg 5-FU) had the highest Bax protein expression; (d and e) PN-treated rats (30 and 60 mg/kg PN) showed higher Bax proteins (intense brown colour) with less mucosal damage than that of cancer controls. (Magnification, 100×). Values are shown as mean ± SEM (n = 6).

ns: non-significant.

**p < 0.01; ****p < 0.0001.