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. Author manuscript; available in PMC: 2023 Dec 9.
Published in final edited form as: J Vis Exp. 2018 Nov 29;(141):10.3791/57849. doi: 10.3791/57849

Figure 1: Overview of the orthotopic model without mastectomy.

Figure 1:

(A) This panel shows a time course of the orthotopic model utilizing the 4T1 syngeneic model. (B) This panel shows the whole-body bioluminescence of an orthotopic model which mainly reflects the primary tumor. The error bar indicates the standard error of the mean (n = 10). (C) This panel shows serial images of whole-body bioluminescence (of the same mouse). The scale bar indicates 1 cm. (D) This panel shows the actual tumor size of panel B, measured by calipers. The error bar indicates the standard error of the mean (n = 10). (E) This panel shows lung ex vivo bioluminescence images of 10 orthotopic model mice (n = 10). The scale bar indicates 1 cm.