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. 2023 Dec 6;16:5845–5864. doi: 10.2147/JIR.S432747

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© 2023 Wang et al.

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Effects of IAld supplementation on gut barrier integrity in a DSS-induced mouse model.

Notes: (A) p65 expression (nuclear fractions) from colonic tissue was measured using immunoblot. Lamin B1 was a loading control. Data are presented as the ratio of p65/Lamin B1. p65 DNA binding activity (nuclear fractions) was determined using p65 Transcription Factor Assay. (B) The intestinal permeability was measured as the FITC-dextran levels in the serum of the mice. (C and D) The expression of and MLCK and p-MLC were measured using immunoblot. Total protein was a loading control. (E) Representative images of immunofluorescent staining of TJ proteins in colonic tissue. The data are shown as the mean ± SEM (n = 5–8/group). *p < 0.05, **p < 0.01, ***p < 0.01.

Abbreviation: ns, statistically non-significant.