Table 2.

Overview of potential target and key population(s) and associated delivery strategy (ies).

Target and key population(s)	Delivery strategy(ies)
LIC - Adult	Very difficult; adult VPD burden and surveillance systems to support vaccine programs lacking; no comprehensive WHO recommendation for adult immunization; vaccine delivery systems are not optimized.[49]
LIC - Pediatric	Key population of interest and established vaccine programs. Vaccine series would be ideally introduced prior to six months of age given epidemiology [31].
MIC – adult	Very difficult; high risk groups of HIV-infected populations and access to vaccine care is more robust. Growing elderly population and traveler markets may exist. Norovirus may be an important vaccine to introduce into these populations and thus could be a pathway [49].
MIC - Pediatric	Vaccination systems are in place for introduction in pediatric populations. Likely alignment with schedule of rotavirus vaccination.
HIC - Adult	Vaccination systems are in place for adult immunizations and high-risk target populations (elderly, hospital workers, education systems, travelers, etc).
HIC - Pediatric	Vaccination systems in place for introduction in pediatric populations.