Table 1.
Characteristics of PA Patients and Controls
| Total PA | Preperimetric PA | Perimetric PA | Controls | P1 Value | P2 Value | P3 Value | |
|---|---|---|---|---|---|---|---|
| Number of eyes (patients) | 45 (40) | 15 (10) | 30 (30) | 24 (24) | |||
| Age, years | 45.5±10.6 | 48.4±6.7 | 44.5±11.6 | 50.3±12.8 | 0.107a | 0.656b | 0.070b |
| Sex, n (%) | 0.182c | 0.001c | 0.766c | ||||
| Male | 18 (45%) | 9 (90%) | 9 (30%) | 6 (25%) | |||
| Female | 22 (55%) | 1 (10%) | 21 (70%) | 18 (75%) | |||
| BCVA, logMAR | 0.0 (0.0, 0.1) | 0.0 (0.0, 0.0) | 0.1 (0.0, 0.2) | 0.0 (0.0, 0.0) | <0.001d | 0.704d | <0.001d |
| Visual field mean defect, dB | 1.8 (−0.4, 6.0) | −0.5 (−1.0, −0.4) | 4.7 (1.8, 8.5) | ||||
| Average RNFL thickness, μm | 100.4±10.7 | 103.2±10.5 | 98.9±10.7 | 105.1±5.0 | 0.014a | 0.523b | 0.015b |
| Nasal RNFL thickness, μm | 72.4±12.0 | 76.9±10.0 | 70.2±12.4 | 76.9±6.2 | 0.045a | 0.997b | 0.020b |
Notes: Normally distributed variables are presented as mean±standard deviation, and variables from non-normal distribution are presented as median (25th percentile, 75th percentile). at-Test. bPost hoc test followed by one-way analysis of variance (ANOVA). cChi-square test. dNon-parametric test. P1 Value = p value of PA versus controls. P2 Value = p value of preperimetric PA subgroup versus controls. P3 Value = p value of perimetric PA subgroup versus controls.
Abbreviations: PA, pituitary adenoma; BCVA, best corrected visual acuity; logMAR, logarithm of the minimum angle of resolution; RNFL, retinal nerve fiber layer.