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. 2023 Nov 27;14:1245421. doi: 10.3389/fimmu.2023.1245421

Figure 7.

Figure 7

The interaction between TAMs and BCSCs. Representative image of the interaction between TAMs and BCSCs. TAMs secrete cytokines like IL-6, IL-8, and IL-10 and growth factor EGF, promoting self-renewal, expansion, drug resistance, and overall stemness in BCSCs, respectively. BCSCs, on the other hand, secrete CSF-1 that promotes the tumorigenicity of TAMs.