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. 2023 Nov 27;14:1231351. doi: 10.3389/fneur.2023.1231351

Table 3.

Demographics and disease characteristics of the study population irrespective of the presence of headache.

Total (n = 21,480)
Age, years
Mean ± SD 48.8 ± 10.5
19–29 years 1,151 (5.4)
30–39 years 2,944 (13.7)
40–49 years 6,095 (28.4)
50–59 years 8,265 (38.5)
≥60 years 3,025 (14.1)
Sex
Men 15,802 (73.6)
Women 5,678 (26.4)
Headache 7,311 (34.0)
Number of headache days in the past 30 days a
Mean ± SD 3.6 ± 4.7
0–3 days 5,387 (73.7)
4–7 days 1,082 (14.8)
8–14 days 488 (6.7)
≥15 days 354 (4.8)
Physician visita 735 (10.1)
Use only OTC drugs for headachesa 2,859 (39.1)
Migraine based on survey responses (ICHD-3) b
Total 691 (100.0)
Episodic migraine 672 (97.3)
Chronic migraine 19 (2.7)
Diagnosis records c
Migraine 250 (1.2)
Tension-type headache 89 (0.4)
Premenstrual migraine 0 (0.0)
Comorbidity c
Hypertension 3,461 (16.1)
Cardiovascular disorders 1,321 (6.1)
Cerebrovascular disorders 534 (2.5)
Epilepsy 149 (0.7)
Gastrointestinal disorders 6,099 (28.4)
Constipation 1,055 (4.9)
Mood disorders 906 (4.2)
Anxiety disorders 479 (2.2)
Asthma 1,046 (4.9)
Prescriptions c
Acute medications (triptans, acetaminophen, and NSAIDs) 5,609 (26.1)
Prophylactic medications (valproic acid, topiramate, propranolol, lomerizine, and candesartan) 1,598 (7.4)

Data are n (%) unless otherwise stipulated.

a

Proportions were calculated using 7,311 people with headache as the denominator.

b

Proportions were calculated using 691 people with migraine according to the ICHD-3 criteria as the denominator.

c

Data were obtained from medical claims. ICHD-3, International Classification of Headache Disorders, version 3; NSAIDs, non-steroidal anti-inflammatory drugs; OTC, over the counter; SD, standard deviation.