Table 1.
Correlation of gut microbiome between uric acid and intestinal permeability at genus levels.
| Gut bacteria | Uric acid | Intestinal Permeability | ||
|---|---|---|---|---|
| R value | p value | R value | p value | |
| Parasutterella | −0.695 | 0.000 | −0.429 | 0.006 |
| Akkermansia | −0.481 | 0.002 | −0.680 | 0.000 |
| Muribaculum | −0.492 | 0.001 | −0.342 | 0.031 |
| Parabacteroides | −0.389 | 0.013 | −0.432 | 0.005 |
| Bacteroides | −0.327 | 0.039 | −0.571 | 0.000 |
| Coprobacillus | −0.310 | 0.052 | −0.511 | 0.001 |
| Lachnoclostridium | −0.247 | 0.125 | −0.572 | 0.000 |
| Alloprevotella | −0.233 | 0.148 | −0.420 | 0.007 |
| Uncultured_bacterium_o_Mollicutes_RF39 | 0.680 | 0.000 | 0.674 | 0.000 |
| Anaeroplasma | 0.630 | 0.000 | 0.684 | 0.000 |
| Candidatus_Saccharimonas | 0.565 | 0.000 | 0.638 | 0.000 |
| Uncultured_bacterium_f_Clostridiales_vadinBB60_group | 0.565 | 0.000 | 0.679 | 0.000 |
| Uncultured_bacterium_f_Ruminococcaceae | 0.503 | 0.001 | 0.098 | 0.547 |
| Ruminococcaceae_UCG-014 | 0.522 | 0.001 | 0.532 | 0.000 |
| Ruminococcaceae_UCG-005 | 0.471 | 0.002 | 0.421 | 0.007 |
| Oscillibacter | 0.468 | 0.002 | 0.101 | 0.535 |
| [Eubacterium]_xylanophilum_group | 0.465 | 0.003 | 0.392 | 0.012 |
| Ruminiclostridium | 0.451 | 0.003 | 0.275 | 0.086 |
| Desulfovibrio | 0.437 | 0.005 | 0.577 | 0.000 |
| Rikenellaceae_RC9_gut_group | 0.401 | 0.010 | 0.363 | 0.021 |
| Odoribacter | 0.297 | 0.063 | 0.472 | 0.002 |
| Uncultured_bacterium_f_Erysipelotrichaceae | 0.242 | 0.133 | 0.550 | 0.000 |
| Roseburia | 0.213 | 0.187 | 0.405 | 0.009 |
| Enterorhabdus | 0.216 | 0.182 | 0.652 | 0.000 |
Correlation between variables was analyzed by Spearman’s R coefficient. R represents a linear correlation between the two variables. The closer the absolute value of. r is to 1, the stronger the linear correlation between the two variables. R > 0 is positive correlation, R < 0 is negative correlation. p < 0.05 was considered a significant difference.