Comparison 2. Duloxetine versus pregabalin in the treatment of painful diabetic neuropathy.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Number of participants with ≥ 50% improvement in pain at 12 weeks or less	1	804	Risk Ratio (M‐H, Fixed, 95% CI)	1.46 [1.19, 1.80]
2 Mean improvement in pain at 12 weeks or less	1	804	Mean Difference (IV, Fixed, 95% CI)	‐0.62 [‐0.92, ‐0.32]
3 Number improved ≥ 30% at 12 weeks or less	1	804	Risk Ratio (M‐H, Fixed, 95% CI)	1.42 [1.20, 1.68]