Table 3.

Diagnostic signs of potential PH in ILD.

Test	Finding
PFTs	DLCO < 30% or worsening DLCO in the setting of preserved lung volumes
6MWT	Marked or worsening desaturation Severely reduced or worsening 6MWT distance Impaired (decreased) heart rate recovery after exercise (<13)
CT Scanning	Increased PA:A ratio (>0.9) RV:LV ratio > 1
Echocardiography	RVSP elevation > 45 RV dilation Reduced TAPSE RVOT diameter > 4.3 Reduced RV fractional area change Reduced RV ejection fraction on 3‐D echocardiography
Laboratory testing	Elevated BNP

Abbreviations: 3‐D, 3‐dimensional; 6MWT, 6‐min walk test; BNP, brain natriuretic peptide; DLCO, ¼ diffusing capacity of the lung for carbon monoxide; ILD, interstitial lung disease; LV, left ventricular; PA:A, pulmonary artery to aorta; PFT, pulmonary function test; RV, right ventricular; RVOT, RV outflow tract; RVSP, RV systolic pressure; TAPSE, tricuspid annular plane systolic excursion.