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. 2023 Oct 27;51(22):12092–12110. doi: 10.1093/nar/gkad936

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© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Viral chromatin looping is altered by PARP1 inhibition. (A) Circular visualization of the interactions derived from HiC matrices in YCCEL1 cell line. The arches represent the DNA-DNA interactions at 1 kb scale. The blue arches represent the interactions found more frequently in the control samples, while the red ones represent those found more frequently in the Olaparib treated samples (FDR < 5%). (B) Circular visualization (as described in A) of the interactions derived from HiC matrices in SNU719 cell line. In all plots CTCF ChIP-seq track is represented in yellow on top of the arches.