Table 2.
Univariate analysis of differences between patients with and without liver abnormalities detected during pregnancy before their PSC diagnosis.
| Liver abnormalities (n = 21) | No liver abnormalities (n = 146) | p value | |
|---|---|---|---|
| Age at PSC diagnosis, median (IQR), years | 34.6 (32.1-39.3) | 40.7 (32.3-48.8) | 0.06 |
| Age at delivery, median (IQR), years | 30.7 (27.7-35.2) | 28.6 (25.1-31.4) | 0.09 |
| Interval between delivery and PSC diagnosis, median (IQR), years | 1.4 (0.5-5.7) | 7.0 (2.0-18.0) | 0.002 |
| Large duct PSC | 19 (90.5%) | 113 (77.4%) | 0.25 |
| IBD | 10 (47.6%) | 75 (51.4%) | 0.75 |
Continuous variables are expressed as median (IQR), categorical variables are represented as number (%). Subgroup differences were analysed using the Χ2 or Fisher’s exact tests for categorical parameters, and the Mann-Whitney U test or Kruskal Wallis test for continuous variables. IBD, inflammatory bowel disease; PSC, primary sclerosing cholangitis.