Table 3.
Hazard ratio for events (LT or death) during follow up in patients with pregnancy before their PSC diagnosis.
| Univariate analysis |
Multivariate analysis |
|||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p value | HR | 95% CI | p value | |
| Age at PSC diagnosis | 0.89 | 0.85-0.93 | <0.001 | 0.89 | 0.84-0.94 | <0.001 |
| Age at delivery | 1.02 | 0.95-1.09 | 0.57 | |||
| Large duct PSC | 6.23 | 1.49-26.21 | 0.01 | 5.16 | 1.13-23.51 | 0.03 |
| IBD | 3.22 | 1.55-6.66 | 0.002 | 1.46 | 0.64-3.30 | 0.36 |
| Worsening liver-related symptoms during pregnancy | 3.32 | 1.33-8.29 | 0.01 | 1.10 | 0.43-2.85 | 0.84 |
Multivariate logistic regression analysis was performed to assess which features were of independent significance. Variables with a p value of <0.2 and those of particular interest were included. Results were recorded as hazard ratio (HRs) with 95% CIs and p values. IBD, inflammatory bowel disease; PSC, primary sclerosing cholangitis.