Fig. 4.

The human liver cell-type composition.

(A) Average proportions of the major hepatic cell-type fractions, as determined by the RNA-seq-based CIBERSORTx analysis in 138 human liver biopsies. Data are shown as mean ± SD. (B) Association between histological steatosis and the fraction of hepatocytes in human liver biopsies. Regression line was fit using a quadratic model after log-transforming the liver fat fraction. The dashed lines denote 95% CI. The Spearman correlation coefficient is shown. NK, natural killer.