Table 4.
Multivariable analysis of associations with significant fatigue
| Parameters | Univariate analysis | Multivariate analysis | ||
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Female | 2.10 (0.69 to 6.43) | 0.26 | – | – |
| Self-reported active SLE | 4.55 (2.63 to 7.89) | <0.0001* | 2.26 (1.17 to 4.40) | 0.02* |
| Clinically significant pain | 5.68 (3.26 to 9.90) | <0.0001* | 2.83 (1.44 to 5.54) | 0.002* |
| Positive score FiRST | 4.87 (2.67 to 8.85) | <0.0001* | 2.50 (1.26 to 4.96) | 0.008* |
| Clinical anxiety | 2.24 (1.27 to 3.96) | 0.006* | 0.94 (0.46 to 1.93) | 0.88 |
| Clinical depression | 4.14 (1.75 to 9.80) | 0.0003* | 1.92 (0.74 to 4.99) | 0.18 |
| Clinical insomnia | 4.46 (2.45 to 8.11) | <0.0001* | 3.31 (1.73 to 4.34) | 0.0003* |
| High level of stress | 3.71 (2.15 to 6.41) | <0.0001* | 1.97 (1.01 to 3.83) | 0.045* |
| Low level of physical activity | 1.42 (0.81 to 2.48) | 0.27 | – | – |
*P value<0.05; R² for multivariable model: 0.23.
FiRST, Fibromyalgia Rapid Screening Tool; SLE, systemic lupus erythematosus.