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. 2000 Dec;173(6):398–402. doi: 10.1136/ewjm.173.6.398

Table 1.

Factors associated with unfavorable prognosis in multiple sclerosis
  • Male sex

  • Older age at onset

  • Motor or cerebellar signs at onset

  • Short interval between initial and second attack

  • High relapse rate in early years

  • Incomplete remission after first relapses

  • Early disability

  • High lesion load detected by early magnetic resonance imaging of the brain