Table 1.
Management protocols in 6 chest pain evaluation units
| Study, year | Duration of protocol, hr | ECG | Biochemical markers | Additional testing |
|---|---|---|---|---|
| Zalenski et al,9 1997 | 12 | 0, 6, and 12 hr | CK-MB at 0, 4, 8, and 12 hr | Exercise tolerance testing (ETT) |
| Gibler et al,10 1995 | 9 | Continuous ST segment monitor | CK-MB at 0, 3, 6, and 9 hr | 2-dimensional echo, ETT |
| Hoekstra et al,11 1994 | 9 | Continuous ST segment monitor | CK-MB at 0, 3, 6, and 9 hr | Thallium ETT |
| Doherty et al,12 1994 | 9 | 0, 3, 6, and 9 hr | CK-MB at 0, 3, 6, and 9 hr | Cardiology consultation, ETT, thallium ETT, MUGA scan |
| Mikhail et al,13 1997 | 8 | Continuous ST segment monitor | Total CK at 0 hours; with or without CK-MB at 0, 4, and 8 hr; with or without myoglobin at 0 and 4 hr | ETT, stress echo, dobutamine echo, thallium ETT |
| Gomez et al,14 1996 | 9 | Continuous ST segment monitor | Total CK and CK-MB at 0, 3, 6, and 9 hr | ETT, dobutamine echo |
| ECG = electrocardiography; CK-MB = creatine kinase—muscle-brain isoenzymes; echo = echocardiography; MUGA = multigated angiocardiography. | ||||