Table 2.
Gene editing for EV engineering
| No. | Engineered materials | Method | Targeting cell | Ref. |
|---|---|---|---|---|
| 1 | PDGFR-RVG, hnRNPA2B1expressed/mirSilencer | lentivirus | HEK293T | [51] |
| 2 | RVG/BDNF | lentivirus | HEK293T | [52] |
| 3 | SERPINA5 protein | lentivirus | HEK293 | [57] |
| 4 | Serpin protein | lentivirus | HEK293 | [58] |
| 5 | miR-146a | lentivirus | PMSC | [56] |
| 6 | miR-214-3p | lentivirus | UCMSC | [55] |
| 7 | miR-133-3p | lentivirus | UCMSC | [54] |
| 8 | Tat protein | Lipofectamine | HEK293T | [59] |
| 9 | Ldlr mRNA | Lipofectamine | HEK293T | [60] |
| 10 | Protein drug (srIkB) | Effectene Transfection Reagent | HEK293T | [61] |
| 11 | Protein drug (srIkB) | Effectene Transfection Reagent | HEK293T | [62] |
| 12 | Protein drug (srIkB) | Effectene Transfection Reagent | HEK293T | [63] |