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Poliovirus caught in the act. (a) Cryo-EM image of poliovirus interacting with 50 nm covalently circularized nazanodiscs containing CD155 receptor. (b) Tilted views of the nanodisc were observed in ice. (c) Cryo-EM image of individual viral particle tethered to nanodisc containing CD155. (d) Schematic of pore formation and RNA release from poliovirus capsid across the bilayer nanodisc.
