Table 5.

Predictors of disease-specific survival (DSS).

Prognostic variable	Hazard ratio (95% CI)	P-value	Multivariate analysis hazard ratio (95% CI)	P-value
N1 disease	1.64 (0.95-2.85)	.076	N/A
Vascular invasion	8.75 (2.00-38.3)	.004	1.10 (0.50-14.3)	.91
Extrathyroidal extension	5.37 (2.05-14.1)	<.001	4.69 (0.69-33.5)	.12
Biochemical cure	0.83 (0.20-1.72)	.08	N/A
High pathological grade	19.2 (3.66-100.5)	<.001	20.7 (2.1-205)	.010
Metastatic disease	15.5 (5.75-41.7)	<.001	13.6 (2.1-87.4)	.006
Local recurrence	0.41 (0.13-1.27)	.12	N/A
Age	1.03 (0.97-1.08)	.38	N/A
Germline RET mutation	0.91 (0.34-2.45)	.86	N/A

Abbreviation: RET: rearranged during transfection gene.