Table 1.
Baseline patient demographics and tumor characteristics, categorized by tumor location
| Characteristic | Within 3 mm of disc and/or fovea (n = 163) | >3 mm from disc and fovea (n = 59) | All patients (n = 222) |
|---|---|---|---|
| Age at time of PBI, years, median (range) | 60.4 (27.1–94.8) | 62.1 (21.3–81.4) | 60.7 (21.3–94.8) |
| Sex, female, n (%) | 96 (58.9) | 33 (55.9) | 129 (58.1) |
| Tumor thickness, mm, median (range) | 2.0 (1.2–2.5) | 2.0 (1.2–2.5) | 2.0 (1.2–2.5) |
| LBD, mm, median (range) | 8.0 (4.0–10.0) | 9.0 (6.0–10.0) | 8.0 (4.0–10.0) |
| Distance from optic disc, mm, median (range) | 1.35 (0–6.75)* | 6 (3.75–10.5)* | 2.25 (0–10.5) |
| Distance from fovea, mm, median (range) | 1.1 (0–7.5)** | 7.5 (3.5–10.5)** | 1.95 (0–10.5) |
| Baseline logMAR VA ≤0.7 (20/100), n (%) | 145 (88.9) | 59 (100) | 204 (91.9) |
| Follow-up time for ocular outcomes, years, median (range) | 6.1 (1.0–30.2) | 9.9 (1.9–30.1) | 6.9 (1.0–30.2) |
| Follow-up time for survival, years, median (range) | 13.1 (1.5–30.2) | 15.8 (2.2–30.1) | 13.7 (1.5–30.2) |
| Total radiation dose, 70 Gy (RBE), n (%) | 107 (65.6) | 56 (94.9) | 163 (73.4) |
PBI, proton beam irradiation; VA, visual acuity.
*1 missing; **2 missing.