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. 2023 Aug 10;9(6):469–484. doi: 10.1159/000533296

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© 2023 The Author(s). Published by S. Karger AG, Basel

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Fig. 1. — Major process of endogenous biosynthesis and exogenous uptake of polyamines. ODC1, ornithine decarboxylase 1; SRM, spermidine synthase; SMS, spermine synthase; SMOX, spermine oxidase; SAT1, spermidine/spermine N(1)-acetyltransferase 1; PAOX, peroxisomal N(1)-acetyl-spermine/spermidine oxidase; METK, S-adenosylmethionine synthase; AdoMet, S-adenosylmethionine; dcAdoMet, decarboxylated S-adenosylmethionine; AdoMetDC, adenosylmethionine decarboxylase; 3-AAP, 3-acetamidopropanal; AZIN, antienzyme inhibitors; OAZ, ODC antienzymes. Created with BioRender.com.